Vol. 7, Issue 1, Part A (2025)

Background: Osteopenia and osteoporosis are prevalent in inflammatory bowel disease (IBD) patients according to dual-energy X-ray absorptiometry (DEXA) scans. In IBD patients, vitamin D deficiency has been observed.

Objective: We wanted to see if there was a link with both vitamin D deficiency and lowered bone density in (IBD) patients.

Methodology: The current prospective clinical study included (124) IBD patients; (58) diagnosed with ulcerative colitis (UC) and (66) with Crohn's disease (CD). Demographic information, disease subgroups, vitamin D levels, and DEXA scan results were all collected.

Results: In total study population; (35.48%) were normal, (44.35%) were osteopenic and (20.16%) were osteoporotic. There was no significant difference between CD patients and UC patients regarding osteopenia and osteoporosis. There were statistically significant differences among normal BMD, osteopenia and osteoporosis groups regarding body mass index (BMI), age, disease duration and vitamin D level (p<0.001).

Conclusion: Low bone mineral density (BMD) is linked to (IBD). Vitamin D deficiency, (BMI), age and disease duration are primary significant risk factors in IBD patients with osteopenia and osteoporosis.